Still called "attack", "stroke" "Congestion" or earlier "apoplexy", stroke or stroke is now the second leading cause of death worldwide and the third in France where she is also the leading cause of acquired physical disabilities and the second cause dementias. As for cost, it amounts to more than 4% of health expenditure in developed countries. Overall, stroke, whose main cause is hypertension, are divided into two main types: ischemic stroke and hemorrhagic stroke. The first type are the most frequent accounting for 80% of all Stroke. They are due to occlusion of a cerebral artery or to the brain (carotid or vertebral arteries). The second type is caused by a ruptured blood vessel, most often damaged or in poor condition at the origin and subjected to excessive blood pressure. Occlusion or rupture causing an interruption of course from the bloodstream or a reduction in blood flow. So the brain does not receive more than oxygen and nutrients necessary for proper operation. Would then follow damage of varying severity in the patient. Two thirds of people affected by stroke are left with more or smaller.
injections of alpha-linolenic: encouraging results
Facing a stroke caused by a clot, the first thing the specialist will proceed with thrombolysis, which is to dissolve the clot using drug, trombolytique injected intravenously. Yet we would argue that this treatment is effective only 5% of patients and should be completed within 3-4 hours after stroke. However, if a stroke caused by bleeding, the emergency is to stop it and to remove the hematoma that compresses brain tissue. In this context, the work conducted by Carina F. Nguemeni Yonga have significant importance, since the preferred approach would bring forward a solution to both prevention and treatment of stroke. The work she is currently developing as part of his doctoral thesis at the Institute of Molecular and Cellular Pharmacology (IPMC) are in effect to assess experimentally the beneficial effects of alpha-linolenic acid, a fatty acid polyunsaturated, which is part of the family of Omega 3, a stroke or injuries that may result.
"Our work has shown in animals that injection of alpha-linolenic acid leads to a decrease in the volume of brain damage in stroke. We also observed the development of new neurons and new connections between them, this neurogenesis is accompanied by a decrease in oxidative stress that appears after a stroke, "said the young Cameroonian PhD student whose results show that injections of alpha-linolenic acid that can triple the chances of surviving such an accident in post-treatment. results even more interesting and encouraging that information sought from the hospital doctors working in Cameroon especially in stroke, there is a growing incidence of stroke in the African country. "I learned that this type of accident is now affecting people aged 45 years, which is relatively young compared to what is observed in Europe and, more generally, in industrialized countries," says Carine F . Nguemeni Yonga. So certainly if there are statistical work on the subject, little research conducted on the field to explain the increased incidence, which encourages more doctoral student at the back sooner or later to work in his country.
Continue to "mature" before returning home
For now, his path is clear. It goes through a final year thesis in 2011 which lead to the defense of his work and is likely to post-doctoral studies in France or abroad, as nothing is yet decided. "I wish to continue the continuity of my ongoing work, probably at the level of brain diseases, but with different approaches, both theoretical and technical. It's the whole point of post-doctoral studies to be able to acquire new knowledge, "she says. This young woman will therefore "continue his maturation," as she likes to say, overseas, lack of necessary structures in his country's basic research, and take further steps, after graduating in biochemistry at the University of Reims in the Champagne-Ardenne, then Master on the blood physiology at the University of Nice-Sophia-Antipolis, PACA region (Provence Alpes Cote d'Azur).
The homecoming is obvious to Carine F. Nguemeni Yonga that prepares now, searching for contacts, imagining potential collaborations between research teams in Cameroon and foreign teams, especially in education. Also 10,000 euros of the grant that comes from him being given by L'Oreal will serve him well. Recall that to complete his thesis, Carine has received a grant from the Ministry of Higher Education and Research (MoR) French, awarded following a competition. "Without this funding over three years, it would have been impossible to begin this thesis," she admits, noting that until now it was his parents who allowed him to realize this long and exciting adventure. "They fought and bled for me to pay for schooling. It is a chance for me to have." Evidence that, beyond Status of Women, which is sometimes an obstacle in Africa to embark on graduate studies, it is primarily the financial aspects that prevents many girls but also boys, entering. "This award is also the guarantee of access to the network, already high, that is the aggregate stock of previous years, which is essential in terms of visibility for a PhD student like me," she assures .
For more information, contact: Carine
Nguemeni - email: nguemeni@ipmc.cnrs.fr
For Women in Science, website: http://www.femmescience.fr
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